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"Jack Bishop (Simon Baker) lives the life of every man’s dream with his beautiful wife, Amaya, (Paz Vega) and a happy, healthy daughter, Toby (Chloe Moretz). When Toby goes missing, Jack knows his past has come back to haunt him. He also knows the only way he can find her is to use the powers of his long forgotten faith, La Santa Muerte – protectors of the sinner, the worshipers of the dead.
Accompanied by the newly-appointed sheriff and a pair of wary FBI agents, Jack’s search takes him deep into his past, to a psychic who visualizes Jack’s secret in terrifying detail, to the squalid barrios and seediest brothels in Mexico City’s underbelly. But the power of the La Santa Muerte is stronger than he ever imagined, as it reaches out to touch his family and reveals an even darker and unexpected web of lies and deceit."